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HSV-encoded proteins and HSV DNA can be identified within lesional skin of EM, and virally encoded antigens have been detected on keratinocytes.HSV-1 may also infect and reactivate in the cornea.As individual lesions evolve, they become hemorrhagic and then develop a more typical “punched-out” appearance ().

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Mollaret's (aseptic) meningitis is a related condition caused by recurrent HSV-2 reactivation from the sacral ganglia into the spinal cord and meninges, often without accompanying genital lesions.

Patients with AD may suffer acute superimposed eruptions of umbilicated vesicular or pustular lesions due to superinfection by HSV, coxsackievirus, vaccinia virus, and variola virus.

The phenomenon has been referred to as Kaposi varicelliform eruption because of its resemblance to severe varicella infection.

When the causative agent is HSV, the condition is specifically called ; when it is vaccinia, the term eczema vaccinatum is used.

The risk of eczema vaccinatum is one of the primary reasons that smallpox vaccination is contraindicated in patients with AD.


  1. Atopic Eczema, otherwise known as Atopic Dermatitis or Infantile Eczema is a chronic relapsing itchy skin disease. Let us create a treatment plan for you.

  2. Antihistamine use in children Roisin Fitzsimons,1,2 Lauri-Ann van der Poel,1 William Thornhill,3 George du Toit,1,2 Neil Shah,4,5 Helen A Brough1,2

  3. Antihistamines are most commonly used to control the symptoms of allergies. Get expert advice on how they work, possible side effects and are they suitable.

  4. Treatments for Eczema including drugs, prescription medications, alternative treatments, surgery, and lifestyle changes.

  5. A major symptom of eczema is very intense itching. Scratching is a natural response to the itching. However, melanin in brown skin makes it more reactive.

  6. Atopic Dermatitis which is also known as eczema is a common itchy skin disease that typically starts early in infancy or childhood. Schedule an appointment.

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